Testicular Teratoma
Testicular teratomas, classified as non-seminomatous germ cell tumours (NSGCTs), represent diverse tumours with cells from one or more of the...
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Testicular Yolk Sac Tumour
Yolk Sac Tumours (YSTs), also known as endodermal sinus tumours, represent the most common type of testicular germ cell tumours... -
Multiple Endocrine Neoplasia Type 2
Multiple Endocrine Neoplasia Type 2 (MEN2) is a rare inherited disorder characterised by a propensity to develop neoplasms in multiple... -
Testicular Choriocarcinoma
Testicular choriocarcinoma is a highly aggressive, rare nonseminomatous germ cell tumour of the testis, characterised by the presence of trophoblastic... -
Von Hippel-Lindau
Von Hippel-Lindau (VHL) disease is a rare, autosomal dominant, multisystem disorder characterised by the formation of tumours and cysts in... -
BRCA1 & BRCA2
BRCA1 and BRCA2 are human genes that produce tumour suppressor proteins. Mutations of these genes have been linked to hereditary... -
Cowden Syndrome
Cowden syndrome is an autosomal dominant characterised by the development of multiple hamartomas in any organ and an increased risk... -
Multiple Endocrine Neoplasia Type 1
Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary condition characterised by the development of multiple tumours in endocrine... -
Melanoma
Melanoma, primarily seen in fair-skinned, sun-exposed adults, is distinguished by the uncontrolled growth of atypical melanocytes, frequently manifesting the BRAF... -
Testicular Embryonal Carcinoma
Testicular embryonal carcinoma, primarily affecting young adults, is characterised by its complex papillary architecture and typically manifests within a mixed... -
Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer typically presents in a younger demographic than sporadic colorectal cancer, hallmarked by germline mutations in DNA... -
Neurofibromatosis Type 1
Neurofibromatosis type 1 (NF1), also known as von Recklinghausen disease, is a common autosomal dominant disorder characterised by multiple cutaneous... -
Carney’s Triad
Carney Triad is a rare, non-heritable syndrome typically presenting in young females. It comprises of gastrointestinal stromal tumours (GISTs), pulmonary... -
Schwannoma
Schwannoma, known less commonly as neurilemmoma, is a benign peripheral nerve sheath tumour that originates from Schwann cells, which produce... -
Neurofibroma
Neurofibroma is a benign peripheral nerve sheath tumour, typically affecting young adults, associated with neurofibromatosis type 1, characterised by a... -
Li-Fraumeni Syndrome
Li-Fraumeni syndrome is an autosomal dominant cancer predisposition syndrome associated with TP53 mutation. Li-Fraumeni Syndrome (LFS) is an inherited genetic... -
Paraganglioma
Paraganglioma typically presents in adults aged 30-50 years, often with symptoms related to catecholamine secretion or mass effect; pathologically, it... -
Glomus Jugulare
Pulsatile tinnitus and conductive hearing loss. MEN I & II. Aggressive-appearing hypervasular jugular fossa soft-tissue mass extending into middle ear... -
Intracranial Dermoid Cyst
Congenital ectodermal inclusion cyst, usually midline in sellar, parasellar and frontonasal regions Rupture (scattered fat droplets throughout subarachnoid space) can...