Overview
The radial nerve is a major peripheral nerve supplying the posterior portion of the upper limb.


Origin
It originates from the posterior cord of the brachial plexus (C5-T1), in the axilla region
- The location of the cord refers to its relation to the axillary artery – i.e. the radial nerve is posterior to the axillary artery

Course
- From the origin, the radial nerve courses on the posterior wall of the axilla (subscapularis, latissimus dorsi and teres major)
- It then exits the axilla inferiorly via the triangular interval with the profunda brachii artery in the posterior compartment, between long head of triceps and humerus.
- It then descends down the arm within a shallow depression on the surface of the humerus, known as the radial groove (or spiral groove)
- As it descends, the radial nerve wraps around the humerus laterally
- It passes through the lateral intermuscular septa and runs between brachialis and brachioradialis, coursing anteriorly to the lateral epicondyle of the humerus
- It then enters the forearm through the cubital fossa where it divides into terminal branches.
Termination
The nerve terminates by dividing into two branches:
- Deep branch (motor) – innervates the muscles in the posterior compartment of the forearm
- Superficial branch (sensory) – contributes to the cutaneous innervation of the dorsal hand and fingers
Branches
Axilla
Supplies branches to:
- posterior cutaneous nerve of the arm
- branch to long head of triceps
- branch to medial head of triceps
Triangular Interval
- Supplies branches to the long and lateral heads of the triceps brachii
Spiral Groove
Supplies branches to:
- inferior lateral cutaneous nerve of the arm
- posterior cutaneous nerve of the forearm
- branch to lateral head of triceps
- branch to medial head of triceps and anconeus
Lateral intermuscular septa
Supplies branches to:
- Lateral brachialis
- Brachioradialis
- ECRL
- ECRB
Terminal branches
At the level of the radiohumeral joint line, it divides into terminal branches:
- Superficial sensory branch
- Deep branch/PIN
- ERCB branch
Anatomical Variants
- Medial head of triceps may instead be supplied by ulnar nerve
